In This Article
Last updated August 8, 2026 · Reviewed for research accuracy by the MarquePeptides technical team.
What Is BPC-157?
BPC-157 (Body Protection Compound-157) is a synthetic pentadecapeptide — a 15-amino-acid sequence — derived from a fragment of a protein naturally found in human gastric juice. It has become one of the most widely studied research peptides in tissue-repair and gastrointestinal pathway literature over the past two decades.
Research context only: This article summarizes published laboratory and animal-model research. It is not a guide to human use, dosing, or administration. BPC-157 is sold by MarquePeptides strictly for research use only.
Mechanism of Action in Research Literature
Published research on BPC-157 has focused primarily on its interaction with angiogenic signaling pathways and its effects in gastrointestinal tissue-repair animal models. Sikiric et al. (2011) characterized its “stable gastric pentadecapeptide” properties across a range of GI-tract injury models. Later work by Seiwerth et al. (2018) examined its interaction with standard angiogenic growth factor pathways, proposing a role in modulating the VEGF and other growth-factor signaling cascades studied in wound-healing research.
Because BPC-157 is a synthetic fragment rather than a full native protein, in vitro receptor-binding studies remain an active area of ongoing characterization — much of the published literature to date relies on animal models and functional outcome studies rather than fully mapped receptor pharmacology.
Molecular Specifications
| Property | Value |
|---|---|
| CAS Number | 137525-51-0 |
| Molecular Formula | C₂₂H₉₈N₁₆O₂₂ |
| Molecular Weight | 1419.53 g/mol |
| Sequence | Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val |
Full batch-specific purity data and COA are available on the BPC-157 product page.
Laboratory Handling Reference
Like most lyophilized research peptides, BPC-157 should be stored at −20°C prior to reconstitution and used within the stability window noted on its batch COA once reconstituted with bacteriostatic water. See our companion guide, Reconstitution & Storage: A Reference Guide for Research Peptides, for full handling protocols applicable across the catalog.
References
- Sikiric P, et al. “Stable Gastric Pentadecapeptide BPC 157: Novel Therapy in Gastrointestinal Tract.” Curr Pharm Des. 2011;17(16):1612-1632.
- Seiwerth S, et al. “BPC 157 and Standard Angiogenic Growth Factors.” Curr Pharm Des. 2018;24(18):1972-1989.
References provided for research context only. Products sold by MarquePeptides are For Research Use Only — not for human consumption.